TY - JOUR AU - Budish, Eric AU - Roin, Benjamin N AU - Williams, Heidi TI - Do firms underinvest in long-term research? Evidence from cancer clinical trials JF - National Bureau of Economic Research Working Paper Series VL - No. 19430 PY - 2013 Y2 - September 2013 DO - 10.3386/w19430 UR - http://www.nber.org/papers/w19430 L1 - http://www.nber.org/papers/w19430.pdf N1 - Author contact info: Eric Budish Booth School of Business University of Chicago 5807 South Woodlawn Avenue Chicago, IL 60637 Tel: 773/702-8453 E-Mail: eric.budish@chicagobooth.edu Benjamin N. Roin Massachusetts Institute of Technology E-Mail: broin@mit.edu Heidi L. Williams Department of Economics Stanford University 579 Jane Stanford Way Office 323 Stanford, CA 94305 Tel: (650) 723-9303 E-Mail: hlwill@stanford.edu M2 - featured in NBER digest on 2014-01-24 AB - We investigate whether private research investments are distorted away from long-term projects. Our theoretical model highlights two potential sources of this distortion: short-termism and the fixed patent term. Our empirical context is cancer research, where clinical trials – and hence, project durations – are shorter for late-stage cancer treatments relative to early-stage treatments or cancer prevention. Using newly constructed data, we document several sources of evidence that together show private research investments are distorted away from long-term projects. The value of life-years at stake appears large. We analyze three potential policy responses: surrogate (non-mortality) clinicaltrial endpoints, targeted R&D subsidies, and patent design. ER -